Osteoporosis is a common skeletal disease characterized by a reduction in bone strength and increased risk of fractures. Osteoporotic fractures are associated with substantial morbidity, mortality and high healthcare costs. Treatments for osteoporosis have been shown to increase bone strength and reduce fracture risk. The drugs most commonly used to treat osteoporosis are bisphosphonates and calcium supplements. Clinical challenges in using bisphosphonates and Calcium supplements to treat osteoporosis include appropriate selection of patients for initiating therapy. Comparisons between two drugs were done by using paired and unpaired T-test, calculations between before treatment and after treatment. The patient's bone density has been increased in accordance with T-score values obtained from DXA (quantitative ultrasound). A study amongst 60 patients, 50 % of patients are given ibandronic acid and other 50 % patients given calcium, finally, study percentage of Patients - osteoporotic 30% and osteopenia 70% after treatment. The study summarizes that patients who are exposed to ibandronic acids show greater results (BMD) rather than subjects who are exposed to calcium. The study summarizes that oral bisphosphonates show more effectiveness on BMD than calcium supplements for osteoporosis.
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