Camptothecin (CPT) a monoterpene indole alkaloid was extracted from stem bark of Nothapodytes nimmoniana using ultrasonic and microwave assisted extraction technology under different conditions such as surfactant concentration (SC), temperature and exposure time. The optimum parameters for ultrasonic extraction were determined as SC 0.2%, temperature 60 degree for 1 hour. While in microwave extraction, exposure time was reduced up to 2 min at 350 W. By using the optimized parameters, CPT was obtained at 1.645% w/w and 1.654 % w/w for ultrasonic and microwave extraction respectively. The yield of CPT extracted by using surfactant were found to be maximum than those by other solvents and this method was found to be simple, economic, time saving and with high yield.
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