A simple, sensitive, accurate, precise and economical visible spectrophotometric method was developed and validated for the estimation of blonanserin in synthetic mixture. The method is based on the reaction of blonanserin with bromothymol blue dye in dichloromethane giving yellow color chromogen, which shows maximum absorbance at 409 nm against reagent blank. The chromogen obeyed Beer’s law in the concentration range of 1-8 µg/ml for blonanserin. The results of the analysis have been validated statistically and by recovery studies.
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