A simple, precise, accurate, reproducible First order derivative Spectroscopic method was developed for the estimation of Rivaroxaban in bulk and dosage form. The study was conducted in Methanol. The method was found to be linear in the range of 2-12 μg/ml (r2=0.9998) for Rivaroxaban at λmax-238 nm and λmax-291 nm. The proposed method was validated for linearity, precision, accuracy and ruggedness according to ICH guideline for routine estimation purpose of drug in bulk and dosage form. Since the 1st derivative method has been developed and validated to ensure that the performance characteristic of the method meets the requirements for the intended analytical applications.
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