A simple, sensitive and cost effective visible spectrophotometric method has been developed for the determination of Diacerein in capsule dosage form. The method is based on the formation of pink colored chromogen upon dissolving the drug in sodium bicarbonate solution with an absorption maximum of 442 nm. The Beer’s law was obeyed in the concentration range of 0.1 – 160 µg/ml. The proposed method was successfully applied for the estimation of Diacerein in commercially available capsules and the results were statistically calculated and validated. The method was found to be accurate with average percentage recovery of 98.4-99.6. Solution of Diacerein was found to be stable for 2 days under room temperature. The method was found to be rugged and robust.
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