A simple, sensitive, accurate, precise and cost-effective UV spectrophotometric method was developed for estimation of eperisone hydrochloride in tablet dosage form. Optimum conditions for the estimation were established. Shimadzu UV-1800 was used for the purpose. Double distilled water was used as solvent system. Active pharmaceutical ingredient was received with thanks from Sun Pharmaceutical Industries. SKELACT (Sun Pharma, Maharashtra) and RAPISONE tablets (Abbott, Maharashtra) were procured from local market. A wavelength maximum was found to be at 261.40 nm. Beer’s law was found to be followed in the linearity range of 2-20 µg/ml. with molar absorptivity of 14718.93. Validation parameters were also calculated. Student t-test was applied to check any significant difference between labelled claim and experimental values. The method can be successfully applied for routine analysis of eperisone hydrochloride in bulk and tablet dosage form.
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