Journal Scope
Inventi Rapid/Impact: Cosmetic Surgery is the peer reviewed journal of Health Science. Cosmetic surgery is concerned with the improvement of aesthetic appearance of the person. It contains the experimental and theoretical papers related to the cosmetic surgery which includes reconstructive surgery, hand surgery, microsurgery and treatment of burns.
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GENETICS AND MANAGEMENT OF THE PATIENT WITH OROFACIAL CLEFT
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Luciano Abreu Brito, Joanna Goes Castro Meira, Gerson Shigeru Kobayashi, Maria Rita Passos-Bueno
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Cleft lip or palate (CL/P) is a common facial defect present in 1 : 700 live births and results in substantial burden to patients.
There are more than 500 CL/P syndromes described, the causes of which may be single-gene mutations, chromosomopathies, and
exposure to teratogens. Part of the most prevalent syndromic CL/P has known etiology. Nonsyndromic CL/P, on the other hand,
is a complex disorder, whose etiology is still poorly understood. Recent genome-wide association studies have contributed to the
elucidation of the genetic causes, by raising reproducible susceptibility genetic variants; their etiopathogenic roles, however, are
difficult to predict, as in the case of the chromosomal region 8q24, the most corroborated locus predisposing to nonsyndromic
CL/P. Knowing the genetic causes of CL/P will directly impact the genetic counseling, by estimating precise recurrence risks, and
the patient management, since the patient, followup may be partially influenced by their genetic background. This paper focuses
on the genetic causes of important syndromic CL/P forms (van der Woude syndrome, 22q11 deletion syndrome, and Robin
sequence-associated syndromes) and depicts the recent findings in nonsyndromic CL/P research, addressing issues in the conduct
of the geneticist....
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PROTOCOLS IN CLEFT LIP AND PALATE TREATMENT: SYSTEMATIC REVIEW
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Pedro Ribeiro Soares de Ladeira, Nivaldo Alonso
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Objectives. To find clinical decisions on cleft treatment based on randomized controlled trials (RCTs). Method. Searches were
made in PubMed, Embase, and Cochrane Library on cleft lip and/or palate. From the 170 articles found in the searches, 28 were
considered adequate to guide clinical practice. Results. A scarce number of RCTs were found approaching cleft treatment. The
experimental clinical approaches analyzed in the 28 articles were infant orthopedics, rectal acetaminophen, palatal block with
bupivacaine, infraorbital nerve block with bupivacaine, osteogenesis distraction, intravenous dexamethasone sodium phosphate,
and alveoloplasty with bone morphogenetic protein-2 (BMP-2). Conclusions. Few randomized controlled trials were found
approaching cleft treatment, and fewer related to surgical repair of this deformity. So there is a need for more multicenter
collaborations, mainly on surgical area, to reduce the variety of treatment modalities and to ensure that the cleft patient receives
an evidence-based clinical practice....
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THE VARIATION IN THE ABSENCE OF THE PALMARIS LONGUS IN A MULTIETHNIC POPULATION OF THE UNITED STATES: AN EPIDEMIOLOGICAL STUDY
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Ali M Soltani, Mirna Peric, Cameron S Francis, Thien-Trang J Nguyen, Linda S Chan, Alidad Ghiassi, Milan V Stevanovic, Alex K Wong
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The absence of the palmaris longus (PL) has been shown to vary based on body side, gender, and ethnicity. In prior studies,
homogenous ethnic populations have been shown to have differences in rates of absence. However, no study thus far has analyzed
the differences in palmaris longus prevalence in a multiethnic population.We prospectively collected data on 516 patients visiting
the outpatient hand clinics at LAC+USC Medical Center and Keck Medical Center. Analysis of the data was then performed
for variables including ethnicity, laterality, and gender. There were no differences in the absence of the PL based on laterality
or gender. Ethnically, there was no difference between white (non-Hispanic) and white (Hispanic) patients, with prevalence of
14.9% and 13.1%, respectively. However, African American (4.5%) and Asian (2.9%) patients had significantly fewer absences
of the PL than the Caucasian, Hispanic reference group (P = 0.005 and P = 0.008, resp.). African Americans and Asians have
a decreased prevalence of an absent PL. The Caucasian population has a relatively greater prevalence of an absence of the PL.
This epidemiological study demonstrates the anatomic variation in this tendon and may be taken into account when planning an
operation using tendon grafts....
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E- ISSN: Awaited
Inventi Rapid Cosmetic Surgery
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Frequency: Quarterly
E- ISSN: Awaited
RI Factor- 1.0
Abstracted/ Indexed in: Ulrich’s International Periodical Directory & Google Scholar, SCIRUS, getCITED
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