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Inventi Rapid: Pharm Analysis & Quality Assurance
publication date: 2013/1/31

DEVELOPMENT AND VALIDATION OF A STABILITY-INDICATING UV SPECTROSCOPIC METHOD FOR ILAPRAZOLE IN BULK AND PHARMACEUTICAL FORMULATIONS
                  Padhiyar Pratik*, Padaliya Hardik, Bhati Sanjaysinh, Hemant Patel, S S Pancholi

ABSTRACT
A simple, specific, accurate and stability-indicating UV- Spectrophotometric method was developed for the estimation of ilaprazole, using a Shimadzu, model 1800 spectrophotometer and as a solvent methanol used at wave length (?max) 306 nm. Linearity was established for ilaprazole in the range of 2-10 µg/ml. The percentage recovery of was found to be in the range of 99.22-100.21%. The drug was subjected to acid, alkali and neutral hydrolysis, oxidation, dry heat, UV light and photolytic degradation. The proposed method for stability study shows that there was appreciable degradation found in stress condition of ilaprazole.

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How to Cite This Article

Padhiyar Pratik*, Padaliya Hardik, Bhati Sanjaysinh, Hemant Patel, S S Pancholi,  " DEVELOPMENT AND VALIDATION OF A STABILITY-INDICATING UV SPECTROSCOPIC METHOD FOR ILAPRAZOLE IN BULK AND PHARMACEUTICAL FORMULATIONS ",  Inventi Rapid: Pharm Analysis & Quality Assurance ,  Vol. 2013 , Article ID- " Inventi:ppaqa/683/13 " 2013  [ cited 2014 Apr 20 ]  Available From  


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