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Inventi Impact: Med Chem
publication date: 2011/10/15

SYNTHESIS OF SOME OXAZOLONE DERIVATIVES AS ORAL HYPOGLYCEMIC AGENTS
                  Sourav Saha*, Santanu Roy chowdhury, Rajesh Gupta, B.P. Saha

ABSTRACT
A series of novel oxazolone derivatives (3f to 3j) were synthesized by refluxing equimolar quantity of acetyl glycine, substituted aromatic and hetero aromatic aldehyde in presence of acetic anhydride and sodium acetate .The synthesized compounds were screened for oral hypoglycemic activity by alloxan induced model in male Sprague dawley rats. All the compounds were effective except 3h as compared with standard glibenclamide. The results are statistically treated for its significance.

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How to Cite This Article

Sourav Saha*, Santanu Roy chowdhury, Rajesh Gupta, B.P. Saha,  " SYNTHESIS OF SOME OXAZOLONE DERIVATIVES AS ORAL HYPOGLYCEMIC AGENTS ",  Inventi Impact: Med Chem ,  Vol. 2011 , Article ID- " Inventi:pmc/100/11 " 2011  [ cited 2014 Jul 23 ]  Available From  


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